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Hongwu International Group Ltd, with HWNANO brand, is a high-tech enterprise focusing on manufacturing, research, development and processing of nanoparticles,nanopowders, micron powders.

Complementarity in molecular biology involves bringing together pairs of molecules that are mirror opposites of each other that yet fit together perfectly. Think of matching nucleotides within DNA strands. Besides transcribing and repairing genetic information, complementary molecules can be used to deliver bursts of energy by snapping the molecule pairs together. Researchers from University of Miami have developed special self-assembling Carbides Nanoparticles for carrying and depositing complementary particles into living cells.

The Carbides Nanoparticles are made of amphiphilic polymers and are hydrophobic on the inside to help contain the cargo, while being hydrophilic on the outside for safe travel through the body. Being only 15 nanometers in diameter, the Carbides Nanoparticles are small enough to penetrate through cellular membranes. The researchers believe that this technology has wide implications in medicine, including for the delivery and precise activation of drugs only within the interior of cells.

More details from University of Miami:

Essential to this mechanism are the noncovalent bonds that loosely hold the supramolecular constructs together. These weak bonds exist between molecules with complementary shapes and electronic properties. They are responsible for the ability of supramolecules to assemble spontaneously in liquid environments. Under the right conditions, the reversibility of these weak noncovalent contacts allows the supramolecular constructs to exchange their components as well as their cargo.

The experiments were conducted with cell cultures. It is not yet known if the Carbides Nanoparticles can actually travel through the bloodstream.

The next phase of this investigation involves demonstrating that this method can be used to do chemical reactions inside cells, instead of energy transfers..
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Hongwu International Group Ltd, with HWNANO brand, is a high-tech enterprise focusing on manufacturing, research, development and processing of nanoparticles,nanopowders, micron powders.

However, both WC and platinum are heterogeneous catalysts, meaning that they require nanoparticle formulations to create high surface areas and invoke quantum confinement effects to maximize the rates of chemical reactions. While platinum Nitrides Nanoparticles are relatively easy to synthesize, until now, there have been no known methods to synthesize WC Nitrides Nanoparticles less than 5 nanometers and devoid of surface impurities. Tungsten carbide forms at very high temperatures, typically over 800¡ãC (1500¡ãF). These high temperatures cause Nitrides Nanoparticles to sinter into large microparticles with low surface areas. Methods to date that alleviate this agglomeration instead result in Nitrides Nanoparticles
that are covered with excess surface carbon. These surface impurities greatly reduce, or completely eliminate, the catalytic activity of WC.

To solve this problem, the MIT team developed a ¡°removable ceramic coating method¡± by coating colloidally dispersed transition-metal oxide Nitrides Nanoparticles with microporous silica shells. At high temperatures, they show that reactant gases, such as hydrogen and methane, are able to diffuse through these silica shells and intercalate into the encapsulated metal oxide Nitrides Nanoparticles. This transforms the oxide Nitrides Nanoparticles into transition metal carbide (TMC) Nitrides Nanoparticles, while the silica shells prevent both sintering and excess carbon deposition. The silica shells can then be easily removed at room temperature, allowing the dispersal of nonsintered, metal-terminated TMC Nitrides Nanoparticles onto any high-surface-area catalyst support. This is the first method capable of this result.

The team has also been successful in synthesizing the first nonsintered, metal-terminated bimetallic TMC Nitrides Nanoparticles. Electrocatalytic studies have shown that these materials are able to perform hydrogen evolution and methanol electrooxidation at rates similar to commercial PGM-based catalysts, while maintaining activity over thousands of cycles. The catalytic activities obtained were more than two orders of magnitude better than commercial WC powders and WC Nitrides Nanoparticles made by current state-of-the-art synthesis methods that do not prevent sintering or surface carbon deposition..
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