Antibacterial Mechanism of Nano Silver Powder–Most Cost-Effective Antibacterial Material

In nature, harmful bacteria, fungi, viruses and other microorganisms are widely distributed, and they grow, multiply or mutate under certain conditions, which are the main reasons for human infections and diseases. Therefore, the development and application of antibacterial materials and antibacterial products have attracted attention from all over the world. Compared with organic antibacterial agents, inorganic antibacterial agents have the characteristics of high safety, good heat resistance and antibacterial durability; in addition, with the in-depth research of nanotechnology, nanoparticles and nanomaterials have become one of the research hotspots in the field of materials science. , Studies have shown that the antibacterial performance will be greatly enhanced after the nanometerization of the antibacterial agent. Therefore, nano-scale inorganic antibacterial agents have a lot of room for development.

 

Compared with ordinary silver powder, nano-silver power has the unique surface effect, volume effect, quantum size effect and macro-quantum tunneling effect of nano-materials. It has a strong inhibitory and killing effect on dozens of pathogenic microorganisms such as Escherichia coli, Neisseria gonorrhoeae, Chlamydia trachomatis, and will not produce drug resistance. Animal experiments show that even if the amount of this nano-silver antibacterial powder reaches several thousand times the standard dose, the tested animals have no signs of poisoning. At the same time, it also promotes the repair of damaged epithelial cells. It is worth mentioning that the antibacterial effect of this product when exposed to water is increasingly enhanced, which is more conducive to the treatment of diseases.

 

The main application areas of nano silver antibacterial include environmental protection, textiles and clothing, fruit preservation, food hygiene, fibers (fabrics, finished products), information industry, ecological environment, daily necessities, etc. Its detailed applications: cotton, linen, silk, polyester, acrylic, spandex, viscose fiber, protein fiber, finished fabrics, clothing, bedding, daily textiles, toys, etc., aquaculture, gardening facilities, soil improvement, building materials, Decorative materials, detergents, glassware, packaging paper products, paper for special industries, deodorants, antibacterial gels for external use in medicine, and plastic products.

 

Antibacterial mechanism of inorganic nano silver antibacterial agent

The biggest difference between nano-silver inorganic antibacterial agents and organic antibacterial agents is that the use of organic antibacterial agents can easily make bacteria resistant, and improper use can cause harm to the human body, while the use of nano-silver inorganic antibacterial agents will not cause bacteria at any time Produce drug resistance and have antibacterial durability. The antibacterial mechanism generally has the following aspects:

 

  1. The effective ingredients in antibacterial fibers act on cell membrane proteins. It can directly destroy the bacterial cell membrane and cause the cell contents to ooze out. Nano silver and organic antibacterial agents are adsorbed on the cell membrane, hindering bacteria and other microorganisms from absorbing amino acids, uracil and other nutrients necessary for growth, thereby inhibiting their growth.
  2. The far infrared rays emitted from the surface of the antibacterial fabric have a certain wavelength range, which can inhibit the activity of bacteria and cause the death of bacteria.
  3. The surface catalysis of nano-silver affects the normal metabolism and reproduction of bacteria, leading to the death of bacteria.

 

Anti-microbial category

1) Common pathogenic bacteria: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella, etc.

2) Common pathogenic fungi: pathogenic molds such as Aspergillus flavus, Aspergillus nidulans, Penicillium citrinum, etc.; yeasts such as Candida albicans, etc.

3) Common molds that pollute the environment: Aspergillus niger, Aureobasidium pullulans, Paecilomyces variabilis and Trichoderma viride, etc. https://www.hwnanomaterial.com

Nano Silver Powder For Antibacterial Fiber and Fabric phoebe

Fiber can adsorb many microorganisms, such as bacteria, viruses, etc. Most of these microorganisms will multiply very quickly at a suitable temperature, and cause various harm to humans. That is, the normal flora is a conditional pathogenic flora. When the body’s resistance decreases, the harmless normal flora may be transformed into a harmful pathogenic flora. Therefore, adding antibacterial agents to fibers has become a demand for people to pursue a high-quality life. The silver-loaded antibacterial polyester fiber and its textiles have good antibacterial properties against Escherichia coli, Staphylococcus aureus, Candida albicans, MRSA, etc. The antibacterial textile produced by the antibacterial fiber is an effective external barrier lower than that of pathogenic microorganisms invading the human body.

The preparation methods of nano-silver antibacterial textiles mainly include fiber modification method and fabric finishing method. The fiber modification method first adds a suitable antibacterial filler to the fiber-forming polymer, and then performs wet or melt spinning, and then processes it into an antibacterial fabric; the finishing of the fabric is by coating or impregnating an antibacterial agent on the surface of the fabric The way to form an antibacterial layer on the surface of the textile material. Each method has its own advantages and disadvantages, and corresponding processing methods can be used in production according to different needs. At present, the production of antibacterial textiles is mainly based on fiber modification. In this method, the ultrafine nano silver powder of  antibacterial agent is used as an additive for spinning. At this time, the antibacterial agent enters the inside of the fiber, so the washing resistance is good and the antibacterial effect lasts for a long time. Experiments show that spherical nano-silver has a good antibacterial effect. The smaller the size of nano-silver particles, the antibacterial ability of the fabric will be improved. The antibacterial performance of nano silver antibacterial fiber remains unchanged after 50 standard washings. During the processing, the added antibacterial agent must have good compatibility and dispersibility with the fiber body. At the same time, the antibacterial agent particles are small and the particle size distribution range is narrow, which cannot affect the spinning; the addition of additives cannot affect the physical properties of the fiber. Performance, including fiber strength and elongation.

According to the antibacterial performance testing standards established by our country, the colony counting method is usually used for antibacterial testing of textiles. This is a quantitative antibacterial testing method. It can not only observe whether the textiles have antibacterial performance, but also obtain specific antibacterial rate values. At present, the antibacterial performance evaluation methods commonly used in the world include: minimum inhibitory concentration (dilute inorganic antibacterial agents into different concentrations for colonies to quantitatively determine the minimum inhibitory concentration of antibacterial agents against bacteria), minimum sterilization concentration (to determine The lowest concentration method to kill bacteria in a certain period of time), agar diffusion method (a qualitative or preliminary method to determine the antibacterial effect of antibacterial agents) and immersion culture method (a quantitative test of the antibacterial effect of antibacterial textiles) ).

Hongwu produces and supplies nano-silver particles and nano-silver dispersions, which can be customized according to customer requirements. Hongwu Nano has always adhered to market-oriented and technology-driven, and it is its responsibility to meet the reasonable demands of customers. Focus on the industry, deep cultivation and meticulous cultivation. Welcome to cooperate. https://www.hwnanomaterial.com.

Magical nano silver powder — seven antibacterial characteristics

The nanometer (nm) is the smallest unit of measure after the micron, and the nanometer is one millionth of one millimeter, that is to say, nanometer is one billionth of a meter. Nano silver powder is made through cutting-edge nano-technology. The emergence of silver powder in the nanometer state, promotes a qualitative leap of bactericidal ability, very few nano-silver can produce a strong bactericidal effect. It can kill more than 650 kinds of bacteria in a few minutes, with broad-spectrum sterilization and no resistance, whihc can promote wound healing, cell growth and repair damaged cells, without any toxic reactions, find no any stimulus response to the skin. All this opens up a broad prospect application of antimicrobial of nano silver powders,and become the latest generation of natural antibacterial agents. Nano silver sterilization has the following characteristics:

1. Broad spectrum antimicrobial

Nano-silver particles directly into the cell, work with oxygen metabolism enzyme (-SH), make the bacteria asphyxia and death of the unique mechanism of action, which can kill contact with most of the bacteria, fungi, mold, spores and other microorganisms. It has found that it has comprehensive antibacterial activity against drug resistant pathogens such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Enterococcus, and anaerobic bacteria. Fungi such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans and other G +, G-pathogens have bactericidal effects on Chlamydia trachomatis, causing sexually transmitted diseases. Neisseria gonorrhoeae also has a strong bactericidal effect.
An antibiotic can kill about 6 pathogens, while nanoscale silver can kill hundreds of pathogenic microorganisms. Strong effect to kill bacteria, fungi, trichomoniasis, chlamydia / chlamydia, Neisseria gonorrhoeae, bactericidal, the same effect for antibiotic resistance!

2. Potent sterilization

According to the study, it’s found that Ag can kill more than 650 kinds of bacteria in a few minutes. Nano-silver particles and pathogens after the cell wall / membrane binding, can directly into the cell, quickly with the oxygen metabolism of the enzyme thiol (-SH) binding, the enzyme inactivation, blocking the respiratory metabolism to suffocate. Unique bactericidal mechanism, so that nano-silver particles in the low concentration can quickly kill pathogens.

3. Permeability is strong

Nano-silver particles with superior permeability, can quickly penetrate the skin 2mm sterilization, have a good bactericidal effect on the common bacteria, stubborn bacteria, drug-resistant bacteria and fungi caused by deep tissue infection.

4. Repair regeneration

Nano silver can promote wound healing, promote the repair and regeneration of damaged cells, to rot myogenic, anti-bacterial anti-inflammatory to improve the microcirculation around the wound tissue, effectively activate and promote tissue cell growth, accelerate wound healing, reduce scar generation.

5. Antibacterial lasting

Nano-silver particles using patented technology, a layer of protective film, in the human body can be gradually released, so antibacterial effect

6. Safe and non-toxic

As early as the “Compendium of Materia Medica” records: raw silver, non-toxic; US Public Health Bureau in 1990, “on the toxicity of silver investigation report” that: silver on the human body no obvious side effects; nano silver is topical, Is the safest way to use it. According to the experimental study found that mice in the oral maximum tolerance of 925mg / kg, which is equivalent to the clinical use of 4625 times the dose, without any toxic reactions in the rabbit skin irritation experiments, did not find any stimulus response.

7. No drug resistance

Nano-silver is non-antibiotic fungicide: nano-silver can kill a variety of pathogenic microorganisms, stronger than antibiotics, 10nm size of nano-silver particles unique antibacterial mechanism can quickly kill bacteria directly to the loss of reproductive capacity, therefore, can not produce Drug resistance of the next generation, can effectively avoid the resistance caused by recurrent long-term treatment.

Hongwu Nano, an expert in manufacturering in nanopowders since 2002, especialy nano Silver powders with the best antibacterial property.
High purity,99.99%, good shape,spherical, uniform particle size, easy to disperse nano silver powders are supplied.
Generally speaking, the smaller particle size of Ag nanoparticles, the better bactericidal effect.
Silver nanopowders can not only be available for powders state, but also nano silver antibacterial solution, which is ready to be used, is available.
The concentration of nano silver antibacterial solution is 1000PPM commonly. Other concentration of the solution can be customized.

Related Tags:silver nanoparticles antimicrobial   silver nanoparticles applications in medicine