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Nano Diamond Powders for Drug Delivery Applications

Diamond is the hardest substance in the world. Mention it, people often associate it with super hard materials, jewelry and industrial diamond drill bits, grinding wheel. But scientists used the characteristics of nano diamond to delivery successful treat leukemia drug to the pathological cells for malignant tumor treatment.

the new scientific research using nano diamond powders technology has solved the difficult that the tumor cells to discharge the treatment drug to cells in vitro, especially in the process of chemotherapy, the diseased cells resistant, this has been a difficult for the doctors.
The research is published in Nanomedicine: Nanotechnology, Biology
Problem: leukemia cells drug resistance

Daunorubicin is a common drug for leukemia treatment, which treat the illness by slowing down and prevent the growth and proliferation of tumor cell, and eventually kill the diseased cells. But in the process of treatment pathological tumor cells is easy to produce resistance phenomenon to daunorubicin.

Nano diamond intervention therapy

At present, the way that the medical community solve drug resistanc is to develop antibody, but more clinical trials show drug toxicity is big and the effect is not obvious.

In view of this, NUS and UCLA researchers have begun to break through the train of thought, to treat particle size only 2 ~ 8 nm nano diamond powders.

Researchers fix soft erythromycin on the surface of nano diamond, and then put the mixture to diseased cells. The results showed that the nano diamond would be able to bring soft erythromycin into cells and cells haven’t been discharged as before, so as to solve the problems of the diseased cells resistance. Because of nanometer size diamond non-invasive and unique surface features, diamond particles can easily be released into the blood vessels and not causing blocked blood vessels at the same time.

Dr Chow said: “the intervention of nanodiamond greatly improve the possibility of biological adaptability and tolerance combining, and to enhance curative effect. at present, in vivo and in vitro drug safety test results show that the drug with medicinal properties is better, this laid a good foundation for further.

Professor DeanHo added: nano diamond is a very promising treatment carrier on medical research. At present, we will further determine which drugs can be hold by nanometer diamond for specific disease treatment, so as to maximize implement the welfare to patients.
Hongwu International Group Ltd is a collectivize technology company, which is professional manufacturer and supplier for nano carbon series powders including nano diamond powders in small quantity for researchers and in bulk order for industry groups.

Our nano diamond powders size includes <10nm, 30-50nm, 80-100nm, grey powder.
our price is very competitive,espeicially in bulk.

If you’re interested in our nano diamond powders, pls feel free to contact us at hwnano@xuzhounano.com. Thank you!

 

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Research progress of Tungsten carbide cobalt thermal spraying powders and coating

In recent years, the research of the tungsten carbide cobalt thermal spraying with nanostructure coatings become the new trend. as a wear resistant coating, due to its good the hardness and toughness, it is widely used in aerospace, metallurgy, machinery fields. Relative to the hard chromium plating, thermal spraying tungsten carbide cobalt ceramic coating have obvious advantages on abrasion resistance, corrosion resistance, fatigue resistance, what’s more, it have fast preparation speed, low cost, good environment. in some application areas, such as aircraft landing gear, the thermal spraying WC2CoCr coating is replacing hard chrome plating.

Nano structure tungsten carbide cobalt thermal spraying powders preparation from Hongwu nanometer:

1. the precursor solution preparation with soluble salt containing tungsten, cobalt mixing chemical composition.mix them evenly, spray drying, roasting, reduction and carbonization.getting Nanocrystalline WC-Co composite powders;
2. nano structured WC-Co composite powders composition can be adjusted according to the using needs,such as adding some other alloying elements growth inhibitor, and the elements content can be accurately controlled.
3. nano WC-Co composite powders, grain size of WC phase is 60nm with low content of impurities.
4. product technology processes mature sound, own a full set of equipment, low cost, large output, high cost performance.
WC-CO nanoparticles introduction form Hongwu nanometer
1. Particle size:60nm
2. Purity:>99%
3.High hardness
4.High-wearing
5.Ratio: WC:Co=88:12/90:10/94:6, namely, WC-12CO,WC-10CO,WC-6CO
6: Property: High hardness & high-wearing–Tungsten Cobalt alloy nanoparticle have good properties of hardness, strength, high breaking and beating ductility as well as high electrical and thermal conductivity.
The phase composition of the thermal spraying wc-co powder effect on the properties of the coating
high cobalt content in the coating can increase the impact toughness of the coating, its bond strength is also good, and not easy to decarburization, able to work under high temperature without lubrication conditions, and have high abrasion resistance and corrosion resistance.The explosion spraying high cobalt content of cobalt coating tungsten carbide (WC225 % Co) coating applied to aeroengine nozzle, can work long-term reliably under 500 ℃.
Clients application case 1
Low temperature supersonic spraying technology, adopting nano structured WC-Co alloy strengthening coating layer surface, it is not only wear-resistant, corrosion-resistant, but surface smooth level off, structure Compact, high bonding strength with matrix.
Clients application case 2
Nano WC-Co composite powders is successfully used in microbit of PCB, and wear experiments show that  the wear rate with the nanometer WC-Co composite powder is lower 30-40% than the standard microcrystalline drilling bit, its life span is about 2.9 times that of the standard drill.
Tungsten is main raw materials preparation nanometer WC-Co composite powders, in the world only China tungsten resource is rich, about 52% of the world’s total reserves, this is the most advantageous conditions to our company research for researching and development nanometer WC-Co composite powders and alloy. All in all, nanometer WC-Co composite powder has immeasurable potential market.